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How do plant extracts adapt to the trend of healthy aging and longevity applications?
Author : Naturalin Date : Click : times
Chemical drugs often have limitations such as side effects and single efficacy in delaying aging, while plant extracts, as natural, safe and multi-functional active ingredients, have gradually become the focus of attention in the field of healthy aging and longevity due to their unique biological activities. They can intervene in the aging process through multiple pathways, providing strong support for people to achieve healthy aging.
In addition, at the recent Vitafoods Asia 2025 exhibition, Informa Markets revealed dietary supplement trends that entrepreneurs are focusing on, with "healthy aging and longevity" ranking first.
Aging is a complex physiological process involving multiple factors such as oxidative stress, inflammatory response, cellular senescence, and metabolic disorders. Plant extracts are rich in a variety of active components such as polyphenols, saponins, and flavonoids, which can exert anti-aging effects through multiple mechanisms:
Antioxidant Stress
Oxidative stress caused by the imbalance between reactive oxygen species and antioxidant systems in the body is one of the core mechanisms of aging. A large number of reactive oxygen species can damage cellular DNA, proteins, and lipids, accelerating cellular senescence and organ dysfunction. Plant extracts can enhance the body's antioxidant capacity by scavenging free radicals, increasing the activity of antioxidant enzymes (such as superoxide dismutase, catalase), and reducing oxidative damage to cells, thereby slowing down the aging process.
Inhibiting Inflammatory
Response Chronic low-grade inflammation is closely related to the occurrence and development of age-related diseases such as cardiovascular diseases, diabetes, and neurodegenerative diseases. Plant extracts with anti-inflammatory activity can inhibit the production of pro-inflammatory factors (such as tumor necrosis factor - α, interleukin - 6) and reduce the inflammatory response of the body, thereby reducing the risk of age-related diseases and promoting healthy aging.
Regulating Cellular Senescence
Cellular senescence refers to the state where cells lose their ability to divide and proliferate, and accumulate continuously in the body with age, leading to the decline of tissue and organ functions. Plant extracts can regulate the signaling pathways related to cellular senescence, inhibit the occurrence of cellular senescence, or clear senescent cells, thereby maintaining the normal physiological functions of tissues and organs and delaying the aging process.
Improving Metabolic Function
With the increase of age, the body's metabolic capacity gradually declines, which is prone to metabolic disorders such as abnormal blood sugar and blood lipid, and then induces various chronic diseases. Plant extracts can regulate the body's metabolic pathways, improve insulin sensitivity, reduce blood lipid levels, and maintain the balance of material and energy metabolism in the body, laying a solid foundation for healthy aging and longevity.
Recommended Plant Extracts for Healthy Aging and Longevity
Green tea extract is derived from the leaves of Camellia sinensis (L.) O. Ktze., which is rich in catechins, especially epigallocatechin gallate (EGCG), a core active component with strong biological activity.
EGCG has extremely strong antioxidant capacity, which is far higher than that of traditional antioxidants such as vitamin C and vitamin E. It can effectively scavenge free radicals in the body, reduce oxidative damage to cells, and protect the integrity of cell membranes and genetic material. At the same time, EGCG can inhibit the activity of pro-inflammatory enzymes, reduce the release of pro-inflammatory factors, and alleviate chronic inflammation.
Milk thistle extract is obtained from the seeds of Silybum marianum (L.) Gaertn., a plant of the Asteraceae family. Its main active components are silymarin, including silybin, silydianin, silychristin, etc., which are famous for their liver-protecting effects and anti-aging activities.
The liver is an important metabolic organ of the body. With age, the liver function gradually declines, and it is more likely to be damaged by external factors such as drugs, alcohol, and toxins. Silymarin can protect liver cells by enhancing the antioxidant capacity of liver cells, inhibiting the formation of free radicals, and reducing the damage of toxic substances to liver cells. It can also promote the regeneration of liver cells and restore liver function. In addition, milk thistle extract has strong anti-inflammatory effects, which can inhibit the occurrence of chronic inflammation and reduce the risk of age-related diseases such as liver cirrhosis and fatty liver.
Ginseng extract is derived from the roots, stems, and leaves of Panax ginseng C. A. Mey., a plant of the Araliaceae family. It has a long history of application in traditional Chinese medicine for tonifying qi and invigorating the body. Its main active components are ginsenosides, such as Rg1, Rb1, Rg3, etc., which have significant effects on promoting healthy aging and extending lifespan.
Ginsenosides can regulate the body's immune system, enhance the activity of immune cells such as lymphocytes and macrophages, improve the body's resistance to diseases, and reduce the risk of infection in the elderly. At the same time, ginsenosides have strong antioxidant activity, which can scavenge free radicals, reduce oxidative stress damage, and delay the aging of cells and organs. In terms of regulating metabolic function, ginseng extract can improve the body's energy metabolism, enhance physical strength and endurance, and alleviate fatigue in the elderly. It can also regulate blood pressure and blood lipid levels, protect cardiovascular health,which is crucial for maintaining the mental health and quality of life of the elderly.
How to Incorporate Anti-Aging and Longevity-Promoting Plant Extracts into Health Products
For health product manufacturers, integrating anti-aging and longevity-promoting plant extracts into product formulations is a promising direction, but it is necessary to comprehensively consider the following factors to ensure product efficacy, safety, and market adaptability:
Secondly, optimize the concentration of active ingredients. Too low a concentration may not achieve the expected anti-aging effect, while an excessively high concentration may increase the risk of side effects (such as gastrointestinal discomfort caused by excessive EGCG) and increase production costs without significantly improving efficacy. Therefore, it is necessary to determine the optimal concentration through a large number of efficacy and safety tests.
Finally, ensure compatibility with other ingredients. Anti-aging and longevity-promoting plant extracts can be combined with other functional ingredients to achieve synergistic effects. For example, green tea extract can be compatible with resveratrol, coenzyme Q10, etc. to enhance antioxidant and cardiovascular protection effects; milk thistle extract can be combined with turmeric extract, vitamin E, etc. to improve liver protection efficacy; ginseng extract can be paired with astragalus extract, lycopene, etc. to enhance immunity and anti-aging effects. However, during the formulation process, compatibility tests must be carried out to ensure the stability of the product, avoid potential chemical reactions between ingredients, and ensure the safety and efficacy of the product.
Plant extracts such as green tea extract, milk thistle extract, and ginseng extract have become important natural ingredients in the field of anti-aging health products due to their multi-faceted anti-aging mechanisms and high safety. They can effectively resist oxidative stress, inhibit inflammatory responses, regulate cellular senescence, and improve metabolic function, providing strong support for people to achieve healthy aging and extend their healthy lifespan.
References
1. Journal of Agricultural and Food Chemistry, 2022, Research on the antioxidant and anti-aging effects of green tea extract.
2. Phytomedicine, 2021, Meta-analysis of milk thistle extract in liver protection and anti-aging.
3. Journal of Ethnopharmacology, 2023, Study on the effect of ginseng extract on regulating immune function and delaying aging.
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