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Evidence that Lion's Mane mushroom extract promotes emotional health
Author : Naturalin Date : Click : times
Lion's Mane Mushroom Extract
Lion's Mane mushroom (Hericium erinaceus) is a prized edible and medicinal fungus; its flesh is snow-white and its appearance resembles monkey fur, making it a traditional mountain delicacy. Lion's Mane extract is a highly active, concentrated powder produced from the fruiting bodies or mycelia of the mushroom through water or alcohol extraction, followed by concentration and drying.
A study evaluated whether depression, anxiety, sleep disorders, and binge eating disorder improved in overweight or obese individuals following an 8-week supplementation with lion's mane mushroom alongside a low-calorie diet:
Eight weeks of oral erinaceus decreased depression, anxiety, and sleep disorders. erinaceus improved mood disorders of a depressive-anxious nature and the quality of the nocturnal rest. erinaceus increased circulating pro-BDNF levels.
(a) Mean score values ± SEM obtained by means of SCL-90 in H. erinaceus group before (T0), after (T1), and in erinaceus wash-out condition (T2) in (DEP), anxiety (ANX), and sleep disorders (SLEEP). (b) Patients selected for symptomatology before (T0), after (T1), and in erinaceus wash-out condition (T2). The ∗p<0.05 and ∗∗p<0.01 obtained by the comparison versus T0 (according one-way ANOVA, Tukey post hoc test). The comparison of values between T1 and T2 does not show any statistically significant differences.
Depression, anxiety, and sleep disorders decreased significantly according to the SCL-90 after 8 weeks of oral supplementation with H. erinaceus (Figure 3(a)). In particular, depression symptomatology decreased by 34.9% and 36% at T1 and T2, respectively. As concerned anxiety symptomatology, after erinaceus supplementation, we measured a score decrease by 49.6% at T1 and it was maintained at 41.9% at T2. Sleep disorders improved 34.4% at T1 and decreased by 39.1% at T2. Notably, there was no wash-out effect after 8 weeks of the erinaceus because the improvements in depression, anxiety, and sleep disorders were maintained.
Applications:
- Mushroom coffee
- Gummies
- Capsules
- Tablets
In the realm of mood intervention—dominated by chemically synthesized drugs—Lion's Mane mushroom extract represents a possibility: that nature may hold gentler, wiser solutions, simply waiting for us to discover and validate them.
Reference:
Vigna, L., Morelli, F., Agnelli, G. M., Napolitano, F., Ratto, D., Occhinegro, A., Di Iorio, C., Savino, E., Girometta, C., Brandalise, F., & Rossi, P. (2019). Hericium erinaceus improves mood and sleep disorders in patients affected by overweight or obesity: Could circulating pro-BDNF and BDNF be potential biomarkers? Evidence-Based Complementary and Alternative Medicine, 2019, Article 7861297.
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